The first version of the clinical trial simulator is online now.
It uses a dose-response model based on the Hill equation which basically is a saturation model. The assumption is that a cell is covered by a finite number of receptors. When the treatment is applied, a fraction of the receptors (depending on the dosage) is interacting with the treatment molecule and every interaction leads to a response. When every receptor is binding to the treatment, the response saturates.
It's based on the MSToolkit package and is hosted online at shiny apps under
https://mzhku.shinyapps.io/trialsim/
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